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Xu S, Jing M, Kong DM, et al. Chitin binding protein from the kuruma shrimp Marsupenaeus japonicus facilitates the clearance of Vibrio anguillarum[J]. Developmental & Comparative Immunology, 2021(117), 103981.
Journal Developmental & Comparative Immunology IF(2021) 3.636
doi 10.1016/j.dci.2020.103981
Services Peptide Synthesis
A peptide synthesis service was offered by biology company DETAIBIO (Nanjing China),
Sun BQ, Xue YF., Du XL, et al. Identification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis[J]. Veterinary research, 2021(52), 19.
Journal Veterinary research IF(2021) 3.699
doi 10.1186/s13567-021-00900-6
Services Protein purification
The soluble recombinant proteins rRiean_0317, rRiean_0653, and rRiean_1143 were purified by Ni-iminodiacetic acid affinity chromatography (Detai Bio-Tech (Nanjing) Co., Ltd., Nanjing, China)
Li X, Bai LJ, Zhang YH, et al. Novel GLP-1/anti-apolipoprotein B bifunctional fusion protein alleviates diabetes and diabetic complications in combination with low-intensity ultrasound[J]. Life Sciences, 2021(278):119549.
Journal Life Sciences IF(2021) 5.037
doi 10.1016/j.lfs.2021.119549
Services Recombinant Protein Production System Mammalian Expression
All bifunctional fusion proteins were entrusted to Nanjing Detai Bio Co., Ltd. for gene synthesis and recombinant protein expression with purity higher than 98%.
Shao W, Hao ZY, Chen YF, et al. OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma[J]. Journal of molecular cell biology, 2021, 13(6):409-421.
Journal Journal of molecular cell biology IF(2021) 6.216
doi 10.1093/jmcb/mjab001
Services Protein purification
Human p53 protein was purified (Detai Bio)
Huang FY, Sun LY, Zhao C, et al. Protein microcapsules integrated hierarchical scaffolds for local treatment of acute myocardial infarction model[J]. Applied Materials Today, 2021(22), 100901
Journal Applied Materials Today IF(2021) 10.041
doi 10.1016/j.apmt.2020.100901 Product Recombinant ACE2
Services Recombinant Protein Production System Bacterial Expression
Recombinant ACE2 (AA18-740) protein synthetized from E. coli expression system was provided by Nanjing Detai Bio-technology Co, Ltd
Gao DD, Jin N, Fu YX, et al. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors[J]. European Journal of Medicinal Chemistry, 2021(216):113333.
Journal European Journal Of Medicinal Chemistry IF(2021) 6.514
doi 10.1016/j.ejmech.2021.113333 Product STAT3
Services Recombinant Protein Production System Bacterial Expression
Purified STAT3 protein (His-tag 127-722 amino acid, DetaiBio, China)
Feng KR, Wang F, Shi XW, et al. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy[J]. European Journal of Medicinal Chemistry, 2020(201):112428.
Journal European Journal Of Medicinal Chemistry IF(2021) 6.514
doi 10.1016/j.ejmech.2020.112428 Product STAT3
Services Recombinant Protein Production System Bacterial Expression
The STAT3 protein (His-tag 127–722 amino acid, DetaiBio, China)
Zhou T, Zhang W, Cheng DL, et al. Preparation, Characterization, and in vivo Evaluation of NK4-Conjugated Hydroxycamptothecin-Loaded Liposomes[J]. International journal of nanomedicine, 2020(15), 2277-2286.
Journal International journal of nanomedicine IF(2021) 6.40
doi 10.2147/IJN.S243746 Product NK4
Services Recombinant Protein Production
NK4 protein was obtained from Detai Bio-Tech Co., Ltd. (Nanjing, China)
Ma M, Wang LB, Zhang SL, et al. Acid vacuolar invertase 1 (PbrAc-Inv1) and invertase inhibitor 5 (PbrII5) were involved in sucrose hydrolysis during postharvest pear storage[J]. Food Chemistry, 2020(320):126635.
Journal Food Chemistry IF(2021) 7.514
doi 10.1016/j.foodchem.2020.126635 Product PbrII5、PbrAc-Inv1
Services Recombinant Protein Production System Bacterial Expression
proteins of PbrII5, PbrAc-Inv1 and its mutants (Table S2) were enriched through prokaryotic expression and prepared with the aid of nickel affinity chromatography by Nanjing Detai Bio
Wan L, Jin ZQ, Hu B, et al. IL-Y Aggravates Murine Chronic Graft-Versus-Host Disease by Enhancing T and B Cell Responses[J]. Frontiers in Immunology, 2020(11), 559740.
Journal Frontiers in Immunology IF(2021) 7.561
doi 10.3389/fimmu.2020.559740 Product IL-Y
Services Recombinant Protein Production
A total of 1 × 105 naive T cells were cultured for 48 h alone or with 10 μg/ml rIL-Y protein (DETAIBIO, China).
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